Restore a Smoother, Youthful Appearance in New York
BOTOX® on Fifth Avenue, NYC
Dynamic wrinkles appear on the face when you’re expressing emotions. These start off as subtle lines and disappear when your face is at rest. Our habitual expressions or motions, such as smiling and frowning, raising our eyebrows, or wrinkling our nose, along with the natural aging process and other stressors, can cause these wrinkles to deepen over time. They can give you an older or more tired appearance. BOTOX® at New York’s Dr. Dennis Gross Dermatology targets the specific facial muscles that contribute to wrinkles, temporarily reducing them and giving you a more refreshed, energized and youthful-looking appearance.
This minimally invasive injectable procedure targets problem areas without surgery and with little to no downtime, providing natural-looking, subtle results. It can be ideal for younger patients who are starting to see the first signs of aging or others who already have more prominent wrinkles. BOTOX® sessions are easy and convenient – they can usually be fit into a lunch break, and you’re able to return to your normal activities after. By softening wrinkles like frown lines and crow’s feet, BOTOX® leaves you feeling rejuvenated and gives you a boost in confidence. We’ll guide you through each stage of the process, from the first BOTOX® consultation to results and how to preserve your younger-looking appearance.
Ready to explore BOTOX® treatment in new york city?
Soften frown lines, forehead creases, and more with BOTOX® on Fifth Avenue, New York at Dr. Dennis Gross Dermatology. Call us at (212) 725-4555 to schedule or book an appointment online with our team. We serve Manhattan, Queens, Brooklyn, Staten Island, Bronx, and the surrounding communities, including New Jersey and Connecticut.
Dr. Dennis Gross
Decades of Distinction
Behind every treatment is decades of research, training, and expertise. We are dedicated to helping our patients look and feel their best.

25+ years as a board-certified dermatologist and dermatologic surgeon, founder of his 5th Avenue Manhattan practice. A New York Magazine Best Doctor and a trusted voice on national TV, from The Today Show to CNN. He’s also the author of Your Future Face: The Customized Plan to Look Younger at Any Age. 25+ years as a board-certified dermatologist and dermatologic surgeon.
World-Renowned Dermatologist
Founded his award-winning skincare brand in 2000, now carried by Sephora, Nordstrom, and MECCA Beauty. He continues to serve as the brand’s Chief Science Officer.
Founder of Dr. Dennis Gross Skincare™
Before opening his practice, Dr. Gross conducted extensive melanoma research at Memorial Sloan Kettering Cancer Center, studying how the immune system recognizes cancer cells. His findings were published in peer-reviewed journals including the Journal of Experimental Medicine and the Journal of Medical Microbiology.
Skin Cancer Research
A native New Yorker, Dr. Gross has spent his career and personal life rooted in the city he serves. He sits on the Board of Animal Care Centers of NY, championing animal welfare initiatives across the five boroughs, and shares a busy family life in Manhattan with his wife and business partner, Carrie, and their four children.
Beyond the Practice
Our Experts
Your Trusted Experts in Professional Dermatology
Lara Battema, LE, MPH
Lia Trojansky, PA-C
Hilary Reich M.D.
Common Concerns and How BOTOX® Helps
From Facial Wrinkles to Dimpling, Drooping Brows, Square Jaw, and Neck Bands
BOTOX® is FDA-approved for crow’s feet, frown lines, forehead wrinkles, and neck bands. It also has a variety of other cosmetic and medical benefits.
Holistic Wellness
Ideal for those who want to combine skincare with overall well-being, promoting balance, radiance, and healthy glowing skin from the inside out deeply.
Include :
$350/session
How Injectable Wrinkle Relaxers Target Expression Wrinkles and Other Concerns
BOTOX® Procedure Overview
A BOTOX® procedure is a quick, minimally invasive treatment with fast results that is designed to relax targeted facial muscles and soften the appearance of dynamic wrinkles. It begins with a consultation, during which we assess your facial anatomy, discuss your goals, and determine the precise injection sites needed to achieve natural-looking, authentic results. Once a plan is established, the treatment area is cleansed, and a series of small BOTOX® injections are administered using a very fine needle.
Most patients describe the sensation as a brief pinch, and the entire process typically takes about 10 to 20 minutes, making it easy to fit BOTOX® into a busy schedule.
Find Out Who Can Benefit Most from BOTOX® in NYC
Who is a Candidate for BOTOX®?
You may be an ideal candidate for BOTOX® if you have moderate to severe dynamic wrinkles and they are located on areas where BOTOX® can be used, you’re in good general health, and you have realistic expectations for improvement.
What Outcome to Expect from Injectable Wrinkle Treatments in NY
How Long Do BOTOX® Results Last?
The longevity of BOTOX® varies depending on where it’s used, but the average duration for facial wrinkle treatments is three to four months. Your metabolism, muscle strength, and dosage can affect how long BOTOX® lasts.
What to Expect After BOTOX® and How to Care for Your Skin
Downtime and Aftercare for BOTOX®
There is little to no downtime for BOTOX®, so you can return to most normal activities right away, although you may be advised to avoid strenuous exercise, lying down, or touching the treated areas for several hours. Avoid taking blood-thinning medications that can cause bruising at the injection site.
Results from this injectable aren’t instant as it takes time to work on the muscles – they gradually appear over the next few days as the muscles relax, with full effects visible in about one to two weeks. The outcome is smoother, more rejuvenated skin that still allows for natural facial expression.
FAQ
Let’s Talk About Your Skin’s Needs
We’re here to make your skincare journey simple, stress-free, and tailored just for you.
Haven’t got an answer?
Book An Appointment Online.
BOTOX® is a temporary treatment. Results last for three to four months on average. However, the effects do not disappear instantly; they gradually fade over time. Your facial muscles gradually regain movement as your body naturally metabolizes the BOTOX® protein and your normal nerve signals return in the injected area. Your wrinkles return to their pre-treatment state.
BOTOX® temporarily softens and reduces wrinkles by relaxing muscle activity for a limited time, but it does not actually erase fine lines or wrinkles completely. For most patients, BOTOX® is more of a preventative treatment than a restorative one. It can stop your existing dynamic wrinkles from becoming more pronounced, but it won’t make them disappear for good.
BOTOX® can sometimes be used to ward off wrinkles before they become prominent in certain patients. This can be ideal for patients in their mid to late twenties or thirties who are noticing the initial stages of wrinkles. Relaxing the muscles under your skin, it can potentially stop wrinkles from becoming deeper.
BOTOX® delivers natural-looking results that maintain facial expression. The goal is to soften lines, not eliminate movement entirely, so you can still smile, frown, and express yourself without deep creases forming.
To maintain optimal BOTOX® results, follow our aftercare instructions, avoid excessive sun exposure, and keep a consistent treatment schedule every three to four months. A good skincare routine and healthy lifestyle habits can also help prolong smoother, longer-lasting results.
Haven’t got an answer?
Book An Appointment Online.
Find Your Perfect Skincare Plan
Ready to restore a more youthful appearance? BOTOX® on Fifth Avenue, New York City, at Dr. Dennis Gross Dermatology is ideal for facial rejuvenation. Call us at (212) 725-4555 to schedule or book an appointment online with our team.
Explore Alternatives and Complementary Treatments for BOTOX®
Advanced Cosmetic Dermatology Options
At Dr. Dennis Gross Dermatology, we provide a full range of cosmetic skincare solutions. In addition to BOTOX®, we offer a variety of hyaluronic acid (HA) and biostimulatory dermal fillers. Unlike BOTOX®, which works best for dynamic wrinkles, facial fillers add volume to reduce static wrinkles or enhance facial contours and features, such as the cheeks, lips, and jawline. To optimize facial rejuvenation results, we may recommend pairing BOTOX® with HA fillers like JUVÉDERM® or Restylane®. Energy-based treatments such as intense pulsed light (IPL) and laser skin resurfacing, and skin rejuvenation procedures such as chemical peels and HydraFacials help to improve the appearance of wrinkles. These skin treatments enhance your overall skin tone and texture, improving other concerns that can’t be addressed with BOTOX® alone.
Medically Reviewed by Our Dermatology Team
Doctor Review and Patient Care Standards
This page was medically reviewed by the board-certified dermatology team at Dr. Dennis Gross Dermatology, including Dr. Dennis Gross and Dr. Hilary L. Reich. Treatments provided by our dermatologists, medical assistants, aestheticians, and physician associate are tailored to each patient’s needs after an in‑person assessment. The information here is general and not a replacement for a consultation; individual responses and results vary.



